The analytical study of the tissue biocompatibility status of intrauterine contraceptive beta phase Titanium Copper Alloy for gynecological application within the endometrium environment was investigated in comparative analysis with existing monoelement copper prototype Cu-T380(IUD). The biocompatibility assessment of the existing Cu-IUD380 evaluates problems of fragmentation micro-structural load deformation – failure mode which cause expulsion phenomenon , tissue bio-corrosion\u00a0 phenomenon, cell cytotoxicity phenomenon,\u00a0 microbial pathogenic\u00a0\u00a0 skin rash reactions, Pelvic Inflammatory Disorders(PID), with copper allergenic cramp resulting in infection phenomenon. These adverse phenomenal effects of expulsion, corrosion, cytotoxicity and subsequent infection associated with copper Intrauterine Device necessitated the development of an optimally improved beta phase biomaterial alloy, Titanium Copper alloy (TiCu alloy). This research innovated the design and production of Beta((\u03b2) phase TiCu alloy in the categories of specimens; Ti0.5%Cu, Ti1.0%Cu, Ti2.0%Cu, Ti5.0%Cu, Ti10.0.0%Cu, Ti15.0%Cu and Ti17.0% Cu, using Copper element as the experimental control reference biomaterial. The Ti-Cu alloy specimens were produced by powder metallurgy technique in an inert environment. The biocompatibility of the manufactured samples was investigated by Cellular Adhesion Test and Mitochondria (MTT) Activity Test methods. Ti17%Cu recorded a higher cell viability of 155% and 0.029mg\/L copper ion release which establish it (Ti-Cu) as a possible replacement to the existing prototype biomaterial (Cu-T380(IUD).<\/p>\n